home *** CD-ROM | disk | FTP | other *** search
- *****************************************
- * Adipokinetic hormone family signature *
- *****************************************
-
- Adipokinetic hormones (AKH) [1,2] are small active peptides produced by some
- insect species. They bring on the release of diglycerides from the fat body
- and then stimulate the flight muscles to use them as an energy source. Other
- types of active peptides structurally related to AKH are:
-
- - Hypertrehalosaemic factors (HTF), which are neuropeptides that elevate the
- level of trehalose in the hemolymph of some insects.
- - Red pigment concentrating hormone (RPCH), a peptide that stimulates pigment
- concentration in prawn erythrophores.
-
- These peptides are eight to ten amino acid residues long. The signature
- pattern to detect them is based on the sequence of the first eight residues,
- which are common to all these peptides.
-
- -Consensus pattern: Q-[LV]-[NT]-[FY]-[ST]-x(2)-W
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: salmon gonadoliberin.
-
- -Last update: June 1992 / Pattern and text revised.
-
- [ 1] Schaffer M.H., Noyes B.E., Slaughter C.A., Thorne G.C., Gaskell S.J.
- Biochem. J. 269:315-320(1990).
- [ 2] Gade G., Hilbich C., Beyreuther K., Rinehart K.L. Jr.
- Peptides 9:681-688(1988).
-